GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THYM | cis | rs1577917 | 1 | rs12661204 | chr6:86678586 | SNHG5 | chr6:86386726-86388451:- | -0.61 | -7.35 | 6.78E-11 | Response to antipsychotic treatment |
| THYM | cis | rs1577917 | 1 | rs12663651 | chr6:86701655 | SNHG5 | chr6:86386726-86388451:- | -0.57 | -6.89 | 5.95E-10 | Response to antipsychotic treatment |
| THYM | cis | rs1577917 | 1 | rs12663690 | chr6:86640162 | SNHG5 | chr6:86386726-86388451:- | 0.57 | 6.89 | 5.95E-10 | Response to antipsychotic treatment |
| THYM | cis | rs1577917 | 1 | rs12664335 | chr6:86597774 | SNHG5 | chr6:86386726-86388451:- | 0.56 | 6.66 | 1.79E-9 | Response to antipsychotic treatment |
| THYM | cis | rs1577917 | 1 | rs12665321 | chr6:86769289 | SNHG5 | chr6:86386726-86388451:- | -0.62 | -7.46 | 4.09E-11 | Response to antipsychotic treatment |
| THYM | cis | rs1499614 | 1 | rs1267817 | chr7:66110040 | CCT6P1 | chr7:65216092-65228661:+ | 0.59 | 4.86 | 4.58E-6 | Gout |
| THYM | cis | rs1499614 | 1 | rs1267818 | chr7:66107024 | CCT6P1 | chr7:65216092-65228661:+ | 0.59 | 4.86 | 4.58E-6 | Gout |
| THYM | cis | rs2243480 | 1 | rs1267820 | chr7:66050295 | CCT6P1 | chr7:65216092-65228661:+ | 0.59 | 4.86 | 4.58E-6 | Diabetic kidney disease |
| THYM | cis | rs2243480 | 1 | rs12698509 | chr7:65418876 | CCT6P1 | chr7:65216092-65228661:+ | 0.62 | 5.13 | 1.51E-6 | Diabetic kidney disease |
| THYM | cis | rs1395 | 1 | rs1275538 | chr2:27441397 | KCNK3 | chr2:26915581-26954066:+ | -0.51 | -4.44 | 2.45E-5 | Blood metabolite levels |
| THYM | cis | rs2275426 | 1 | rs12760175 | chr1:46447840 | CCDC163P | chr1:45960581-45965646:- | -0.46 | -5.37 | 5.48E-7 | Body mass index |
| THYM | cis | rs12780845 | 1 | rs12771477 | chr10:17209464 | CUBN | chr10:16865966-17171816:- | 0.31 | 4.8 | 5.85E-6 | Homocysteine levels |
| THYM | cis | rs12780845 | 1 | rs12772275 | chr10:17204542 | CUBN | chr10:16865966-17171816:- | 0.3 | 4.68 | 9.61E-6 | Homocysteine levels |
| THYM | cis | rs12780845 | 1 | rs12773642 | chr10:17196055 | CUBN | chr10:16865966-17171816:- | 0.31 | 4.8 | 5.85E-6 | Homocysteine levels |
| THYM | cis | rs12780845 | 1 | rs12780845 | chr10:17223244 | CUBN | chr10:16865966-17171816:- | 0.32 | 5.02 | 2.41E-6 | Homocysteine levels |